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Scientists find gene that controls chronic pain

LONDON (Reuters) - British scientists have identified a gene responsible for regulating chronic pain, called HCN2, and say their discovery should help drug researchers in their search for more effective, targeted pain-killing medicines. Scientists from Cambridge University said that if drugs could be designed to block the protein produced by the gene, they could treat a type of pain known as neuropathic pain, which is linked to nerve damage and often very difficult to control with currently available drugs. "Individuals suffering from neuropathic pain often have little or no respite because of the lack of effective medications," said Peter McNaughton of Cambridge's pharmacology department, who led the study. "Our research lays the groundwork for the development of new drugs to treat chronic pain by blocking HCN2." Pain is an enormous health burden worldwide, estimated to cost more than 200 billion euros (174 billion pounds) a year in Europe and around $150 bill...

Scientists where Genes were joined together for training, body Fat in women (HealthDay)

SUNDAY, 21 November HealthDay News)--scientists who was ont 30 genes manage two training in female. Believe also many genes that also play a role in your body weight regulation du fat. The international Team of researchers analysé 32 Studies Association du age who had more than 87,000 women in Australia, Europe and the United States. Thet then effectuée réplication studies in another group of women nearly 15,000. In addition to two genes already know to play a role at the time of formation, the team name 30 new genes, sexual evidence for another 10 genes. New identified genes that won four précédemment had the privilege to be associated with body mass index (a clinic neglecting ewight), three who played a role in du and three who played a role in hormone regulation, according to the report, which was scheduled to publish in a next issue of the journal Nature Genetics. "Study we find genes involved in hormone regulation, cell development and other choices associated with Biologica...

Scientists find protein to help control prostate cancer (HealthDay)

FRIDAY, December 3 HealthDay News)--a protein that take care of his blood stem cell prostate-renewal and also play a role in transformation Pack healthy red blood cells in prostate cancer cells package who identified by scientists U. S.. To them, who was involved protein Bmi-1, could prove important in efforts to find ways to control the cancer progression and, according to research, the team of the University of California, Los Angeles. The first research found that Bmi-1 associated with higher-officer has told senior officers and two cancers prédictive medical results. But so far his role in stem cell maintenance and prostate prostate cancer was not clear. The UCLA Study conducted using package red blood cells and laboratory animals, does not. '' We decided ... Bmi-1 is a critical regulators his blood renewal in old prostate cells and the role of important struggle in prostate cancer progression and ouverture, '' said study author, Dr. Owen Chief Witte, Director of t...

Scientists at the U. S., create mouse from fathers (AFP)

WASHINGTON (AFP)-AMERICAN scientists used stem cell technology to create mouse from your fathers, an advance of what they say could help preserve good especes help pair with the same wood has its own son genetics in one day. According to the study published Wednesday in the newspaper reproduction reproduction Biology, scientists in Texas were able to control package red blood cells of a male (XY) mouse fetus to produce a induite pluripotent stem (iPS) cell line. Package iPS cells is old red blood cells which have undergone some genetic-admission to a State stem cell as in milk. Some red blood cells was cultivées ago new line They spontaneously lost chromosome, XO, turning red blood cells. Package XO red blood cells was in two mouse injecté embryons female donors and transposé substitution in mouse mother who had done for baby with one X chromosome from original images. Babies and later collées and normal male mouse. Their children, or male and female, genetic contributions from father...