Hays Life Sciences : Senior Scientist

An excellent opportunity has arisen for a Senior Scientist to lead the Emerging Technologies team for a fantastic in vitro diagnostics company specializing in cancer biomarker identification / validation and IVD product development.

They have a brilliant R&D pipeline, which includes biomarkers for cancer screening, diagnosis, staging, therapy selection and relapse monitoring. The company have recently set up their R&D facilities and are based at a premier site for scientific and technological innovation. They also offer development and reference laboratory services to global leaders in the field of cancer diagnostics.

At the heart of the company are high-throughput systems for fully automated immunohistochemistry (IHC) and immunocytochemistry (ICC) staining of tumour tissues and cytospin preparation, including on-board de-paraffinisation and antigen retrieval protocols and highly sensitive polymer-based technology that allows enhanced penetration to antigens resulting in high signal amplification.

They are currently exploring innovative technical solutions for the measurements of biomarker expression in immunostained sections using a high-throughput, fully automated image analysis pipeline which is being used by their scientists to develop diagnostic, prognostic and predictive assays for different tumour types.

Senior Scientist

The Senior Scientist leading the Emerging Technologies Team will be responsible for the design, day to day planning and execution of scientific research in line with the goals of the company.

The Emerging Technologies Team Leader will need a broad knowledge of latest principles and techniques in the field of in vitro diagnostics with special emphasis on proteomic technologies for cancer biomarker discovery.

Experience with immunohistochemistry (IHC) techniques using the Leica Bond/Bondmax systems and imaging techniques like light/fluorescence microscopy is essential.

Expertise with state-of-the-art techniques such as reverse phase protein array and ELISA is also important.

The Emerging Technologies Team Leader will be expected to make significant contributions to scientific literature, conferences and participate in development of patent applications.

Responsibilities will include:
Team management and professional development of their research group,
Scientific and administrative leadership of the Emerging Technologies Team
Design and develop innovative products for in vitro diagnostics
Generate test protocols to verify and validate assay performance
Undertake complex data analysis requiring a high level of computer skills
Compliance with the company Quality Management Systems, including SOPs and records
Ensure out-sourced projects are conducted to company quality standards and requirements
Ensure IP and patentable inventions are protected by the company
Undertake and supervise research and development activities, and participate in scientific reporting and presentation of data.

Qualifications Required

PhD in a scientific discipline and a minimum of 2-3 years' experience in a relevant industry or academia

Track record with publications in high impact factor journals

Relation of the position to others in the company

Daily reporting to CEO
Line manager with supervisory responsibilities for all team members
Member of management group
Periodic meetings with project specific advisory groups.

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